We prospectively studied 223 patients (288 lesions) who underwent elec
tive or bail out implantation of 309 NIR stents (Scimed, Boston Scient
ific Corporation, Galway, Ireland), Most lesions (68.4%) had unfavorab
le characteristics (type B2 or C). Primary success in stent deployment
was achieved in 305 (98.6%), There was no Q-wave myocardial infarctio
n, Emergency coronary artery bypass grafting (CABG) was required in 1
patient and 1 death occurred, Subacute thrombosis rate was 0.4%, Refer
ence diameter was 2.65 +/- 0.67 mm. Minimum luminal diameter (MLD) inc
reased from 0.62 +/- 0.45 to 2.69 +/- 0.57 mm and diameter stenosis de
creased from 78.3 +/- 13.4% to 12.7 +/- 5.9%. Clinical follow-up was p
erformed in the first 135 patients for 5.3 +/- 1.6 months and repeat a
ngiography was undertaken in 35 (16%) with recurrence of symptoms at 4
.6 +/- 1.3 months, Clinical restenosis rate was 9.6%. We conclude that
the NIR coronary stent exhibits favorable performance characteristics
and appears to be safe and efficacious in the treatment of coronary l
esions even in the presence of high-risk characteristics. (C) 1998 Wil
ey-Liss, Inc.