There continues to be controversy concerning the optimal use of the ep
idural route in cancer pain. Although spinal opioids undoubtedly give
long-lasting analgesia with low doses, indiscriminate use cannot be re
commended. Inappropriate indications for the epidural route are report
ed in three patients who required home palliative care. In contrast to
epidural treatment, which caused sa,ere clinical problems, simpler me
asures, including oral and subcutaneous opioids, were able to give ade
quate analgesia and a better quality of life. Education of nursing sta
ff and family is necessary when using opioid epidural analgesia at hom
e. Wide dissemination of World Health Organization (WHO) guidelines am
ong doctors and health-care workers can avoid the use of unnecessary a
nd complicated techniques and improve the treatment of terminally ill
patients suffering from cancer pain. (C) S. Mercadante, 1997.