Hr. Khouzam et al., REMISSION OF CANCER CHEMOTHERAPY-INDUCED EMESIS DURING ANTIDEPRESSANTTHERAPY WITH NEFAZODONE, Psychosomatic medicine, 60(1), 1998, pp. 89-91
Objective: To emphasize the importance of treating a major depressive
episode in an elderly patient with small cell lung cancer (SCLC). Meth
od: A case report is described to illustrate the importance of treatin
g depression in an elderly patient with SCLC undergoing chemotherapy.
Results: During the course of antidepressant therapy with nefazodone,
the patient also experienced a remission of cancer chemotherapy-induce
d emesis. Conclusions: This case report suggests that the remission of
emesis could be related to the 5-hydroxytryptamine (5-HT) antagonisti
c property of nefazodone.