Five cases of infant botulism which occurred during the period from Ma
y 1995 to May 1996 in San Luis, Argentina, are reported. Infant botuli
sm was confirmed in all patients by isolation of Clostridium botulinum
type A from stool culture and by the toxin assay. Toxin was found in
the serum of one of them. All patients required hospitalization with t
reatment consisting of supportive especially respiratory and nutrition
al care. At the time of discharge from the hospital, three patients ha
d a good recovery, although two of them had mild difficulties in sucki
ng or constipation. C. botulinum was not detected in samples of honey
which had been given to two of the patients.