Intraluminal tumor thrombus in great cervical veins as a result of thy
roid carcinoma is extremely rare. Three patients (2 Hurthle cell, 1 pa
pillary carcinoma) were surgically treated for thyroid carcinoma assoc
iated with tumor thrombus in the great cervical veins. Tumor thrombus
in the internal jugular vein due to extension of thyroid carcinoma was
found in these 3 patients. Segmental resection of the internal jugula
r vein was performed in all cases and a tumor thrombectomy from subcla
vian vein was accomplished in 1 patient. Histological examination veri
fied intraluminal tumor thrombus resulting from invasion of thyroid ca
rcinoma in all patients. The postoperative follow-up period ranged fro
m 1 to 2 years. Of 2 patients undergoing completion thyroidectomy, 1 d
ied of distant metastasis, the other underwent reoperation for local r
ecurrence. The patient who had a definitive primary surgical procedure
is free of recurrence. Appropriate initial surgical procedure in rare
cases of thyroid carcinoma associated with intraluminal tumor thrombu
s in great cervical veins seems to improve the clinical outcome of the
disease.