SYNTHESIS AND CONFORMATIONAL-ANALYSIS OF 2 2-OXOPIPERAZINE-CONTAININGTETRAPEPTIDE ANALOGS

Authors
POHLMANN A GUILLAUME D QUIRION JC HUSSON HP
Citation
A. Pohlmann et al., SYNTHESIS AND CONFORMATIONAL-ANALYSIS OF 2 2-OXOPIPERAZINE-CONTAININGTETRAPEPTIDE ANALOGS, The journal of peptide research, 51(2), 1998, pp. 116-120
Citations number
15
Categorie Soggetti
Biology
Journal title
The journal of peptide research → ACNP
ISSN journal
1397002X
Volume
51
Issue
2
Year of publication
1998
Pages
116 - 120
Database
ISI
SICI code
1397-002X(1998)51:2<116:SACO22>2.0.ZU;2-6
Abstract
One unsubstituted and one stereoselectively prepared 3-(S)-substituted -2-oxopiperazine have been used as dipeptide templates to generate tet rapeptide analogues. NMR analysis shows that these tetrapeptide analog ues present an inverse gamma-turn conformation in chloroform. (C) Munk sgaard 1998.