RECURRENT CHROMOSOME CHANGES IN 2 ADULT FIBROSARCOMAS

Citation
J. Limon et al., RECURRENT CHROMOSOME CHANGES IN 2 ADULT FIBROSARCOMAS, Genes, chromosomes & cancer, 21(2), 1998, pp. 119-123
Citations number
13
Categorie Soggetti
Oncology,"Genetics & Heredity
Journal title
ISSN journal
10452257
Volume
21
Issue
2
Year of publication
1998
Pages
119 - 123
Database
ISI
SICI code
1045-2257(1998)21:2<119:RCCI2A>2.0.ZU;2-U
Abstract
Cytogenetic analysis of two adult fibrosarcomas revealed clonal chromo somal rearrangements including unbalanced translocations between chrom osomes 2 and 19, with the same segment, 2q21-qter, translocated onto 1 9p13 in one tumor and 19q13 in another; and partial monosomy of 10q du e to add(10)(q22) and del(10)(q22q25) seen in one tumor each. This is the first description of nonrandom chromosomal changes in adult fibros arcoma. (C) 1998 Wiley-Liss, Inc.