ACCIDENTAL EXPOSURE TO DAILY LONG-ACTING GONADOTROPIN-RELEASING-HORMONE ANALOG ADMINISTRATION AND PREGNANCY IN AN IN-VITRO FERTILIZATION CYCLE

A case of successful pregnancy in an in-vitro fertilization cycle, in spite of an accidental exposure to daily long-acting gonadotrophin-rel easing hormone analogue administration, is reported. The patient under went two intracytoplasmic sperm injection cycles with thawed epididyma l spermatozoa, in which, due to a pharmacist's mistake, ovarian stimul ation was carried out by a combination of long-acting gonadotrophin-re leasing hormone agonist (leuprolide depot) and gonadotrophins. A succe ssful singleton pregnancy was achieved after intrauterine embryo trans fer with the birth of a healthy boy after 38 weeks. We describe the ci rcumstances and results of this clinical case, as well as reviewing th e literature.