INHIBITORY EFFECTS ON EPSTEIN-BARR-VIRUS ACTIVATION OF ANTHRAQUINONES- CORRELATION WITH REDOX POTENTIALS

Authors
KOYAMA J TAGAHARA K OSAKAI T TSUJINO Y TSURUMI S NISHINO H TOKUDA H
Citation
J. Koyama et al., INHIBITORY EFFECTS ON EPSTEIN-BARR-VIRUS ACTIVATION OF ANTHRAQUINONES- CORRELATION WITH REDOX POTENTIALS, Cancer letters, 115(2), 1997, pp. 179-183
Citations number
13
Categorie Soggetti
Oncology
Journal title
Cancer letters → ACNP
ISSN journal
03043835
Volume
115
Issue
2
Year of publication
1997
Pages
179 - 183
Database
ISI
SICI code
0304-3835(1997)115:2<179:IEOEAO>2.0.ZU;2-F
Abstract
The redox potentials have been determined for nine anthraquinones in p hosphate buffer at pH 7.2 by means of cyclic voltammetry. A definite c orrelation has been found between the redox potentials and the inhibit ory effects of the anthraquinones on the EBV-EA activation. It has fur ther been shown that the correlation can be made better by introducing an electronic property, i.e. the atomic charge at O-12 as an addition al parameter. (C) 1997 Elsevier Science Ireland Ltd.