PHEOCHROMOCYTOMA UNMASKED BY AMITRIPTYLIN E

A report is given about a 57-year-old woman with a major depression, m elancholic subtype. While under amitriptyline 75 mg/day no adverse eff ects were observed, im mediately after increasing the dosage to 150 mg /day ''head spasms'' with headache, profuse sweating and arterial hype rtension appeared. The diagnosis of a pheochromcytoma was made and adr enalectomy was performed. This is the first case of unmasking a pheoch romcytoma by amitriptyline; furthermore a connexion was found with the daily dosage of the antidepressant.