Introduction: The best clinical strategy for using ERC combined with L
C is still unknown. Based on a wide discussion of literature reports t
he aim of our study is to critically analyse laparoscopic bile duct ex
ploration and to correlate these data to our prospective study of ''th
erapeutical splitting''. Patients and Methods: In a prospective study
1645 consecutive patients with sympomatic gall stone disease were exam
ined by ultrasound. 309 patients had open cholecystectomy because of p
revious gastric surgery or perforation. Patients with a high probabili
ty of harbouring stones in the common duct or having other related dis
orders like biliary pancreatitis had ERC, EPT and stone extraction. 13
36 patients had attempted LC. Results: At endoscopy 70% of the 260 pat
ients required therapy like EPT and/or stone extraction, 95% consequen
tly had their gallbladder removed laparoscopically. Including the pati
ents with biliary pancreatitis morbidity amounted to 3% with no mortal
ity. In the non-endoscopic group with 1076 patients conversion was 6.8
%, morbidity was 4.3% and mortality 0.09%. Residual stones were found
in 0.5% so far. Conclusion: If selection criteria for bile duct pathol
ogy have a high sensitivity and specificity and endoscopical stone cle
arance rate is high,at present ''therapeutical splitting'' still is th
e method of choice.