Fg. Keller et al., THE USE OF HEPARINASE TO NEUTRALIZE RESIDUAL HEPARIN IN BLOOD-SAMPLESDRAWN THROUGH PEDIATRIC INDWELLING CENTRAL VENOUS CATHETERS, The Journal of pediatrics, 132(1), 1998, pp. 165-167
Routine coagulation screening is unreliable if obtained through a prev
iously heparinized central venous catheter. Screening tests were perfo
rmed on 14 paired peripheral and central venous catheter samples witho
ut and with heparinase. The heparinase treated central venous catheter
samples correlated well with the peripheral samples and can be used t
o atraumatically screen for hemostatic abnormalities.