O. Markovic et N. Markovic, CELL CROSS-CONTAMINATION IN CELL-CULTURES - THE SILENT AND NEGLECTED DANGER, In vitro cellular & developmental biology. Animal, 34(1), 1998, pp. 1-8
Cell cross-contamination in cell cultures is a common problem during c
ell culturing and use. Contamination invalidates research results? com
promises the comparison of results between laboratories, reduces repro
ducibility required in industrial production of cell lines, and may le
ad to unusable therapeutic products. The problem can be solved by incr
easing the awareness of its seriousness and by introducing regular qua
lity control of cell cross-contamination in every laboratory where cel
ls are grown and used.