ITS NOT JUST A PHASE - CRYSTALLIZATION AND X-RAY STRUCTURE DETERMINATION OF BACTERIORHODOPSIN IN LIPIDIC CUBIC PHASES

Authors
GOUAUX E
Citation
E. Gouaux, ITS NOT JUST A PHASE - CRYSTALLIZATION AND X-RAY STRUCTURE DETERMINATION OF BACTERIORHODOPSIN IN LIPIDIC CUBIC PHASES, Structure, 6(1), 1998, pp. 5-10
Citations number
34
Categorie Soggetti
Biophysics,Biology
Journal title
Structure → ACNP
ISSN journal
09692126
Volume
6
Issue
1
Year of publication
1998
Pages
5 - 10
Database
ISI
SICI code
0969-2126(1998)6:1<5:INJAP->2.0.ZU;2-B
Abstract
Utilization of lipidic cubic phases in the crystallization of bacterio rhodopsin (bR) has yielded long sought after crystals that diffract X- rays to 2 Angstrom resolution. The resulting structure provides new in formation on the protein conformation and the mechanism of proton tran slocation. Crystallization of bR via lipidic cubic phases may be a har binger of new membrane protein crystallization strategies.