CHARACTERIZATION OF MARKER CHROMOSOMES BY FISH USING MICRODISSECTED PROBES FROM OLD CARNOY-FIXED CELLS - REPORT OF 2 CASES

Authors
CHINEN Y TOHMA T IZUMIKAWA Y NARITOMI K HIRAYAMA K
Citation
Y. Chinen et al., CHARACTERIZATION OF MARKER CHROMOSOMES BY FISH USING MICRODISSECTED PROBES FROM OLD CARNOY-FIXED CELLS - REPORT OF 2 CASES, JPN J HUM G, 42(4), 1997, pp. 543-549
Citations number
21
Journal title
Japanese journal of human genetics
ISSN journal
09168478 → ACNP
Volume
42
Issue
4
Year of publication
1997
Pages
543 - 549
Database
ISI
SICI code
0916-8478(1997)42:4<543:COMCBF>2.0.ZU;2-1
Abstract
We reported on two patients with a de novo marker chromosome of which the origins were successfully identified by FISH using microdissected probes. These probes were established by microdissections of extra chr omosomal segments from Carnoy-fixed cells stored at -20 degrees C for several years. Using these probes, we could verify partial 1q32 trisom y in a patient with 17p+ as well as partial 16q2 trisomy in another pa tient with 4p+.