Bo. Olutade et al., RACIAL-DIFFERENCES IN AMBULATORY BLOOD-PRESSURE AND ECHOCARDIOGRAPHICLEFT-VENTRICULAR GEOMETRY, The American journal of the medical sciences, 315(2), 1998, pp. 101-109
We examined the racial differences in left ventricular (LV) geometric
pattern in relation to 24-hour ambulatory blood pressure (BP) monitori
ng and the presence or absence of a nocturnal BP dip. Our study confir
ms the blunting of nocturnal BP dip among black hypertensives. Body ma
ss index, rather than race, was a major determinant of left ventricula
r hypertrophy, We did not observe a difference in prevalence of left v
entricular hypertrophy by race. However, left ventricular adaptation t
o hypertension differed in hypertensive black and white individuals; w
hereas most of the white patients with Stage 1-2 hypertension had a no
rmal ventricular pattern, LV concentric remodeling and concentric hype
rtrophy were the most common adaptive ventricular patterns in blacks w
ith Stage 1-2 hypertension. A six-fold higher prevalence of concentric
remodeling was observed in blacks as compared with whites. The impair
ed nocturnal BP dip in blacks may contribute to the different hemodyna
mic pattern. Determinants of myocardial oxygen consumption were signif
icantly higher in black hypertensives.