M. Bognar et al., CHRONIC RECURRENT MULTIFOCAL OSTEOMYELITIS ASSOCIATED WITH CROHNS-DISEASE, The American journal of the medical sciences, 315(2), 1998, pp. 133-135
Chronic recurrent multifocal osteomyelitis (CRMO) was first described
by Giedion in 1972 as a self-limited relapsing noninfectious inflammat
ory condition usually affecting children and adolescents, The associat
ion of CRMO with psoriasis, palmoplantar pustulosis, and SAPHO syndrom
e (synovitis, acne, pustulosis, hyperostosis, and osteitis) has been d
escribed, In this case report, we present a 49-year-old man with CRMO
coexisting with Crohn's disease, To our knowledge, this is the first r
eport of CRMO with Crohn's disease without the presence of pustular sk
in lesions or other features of SAPHO syndrome.