Et. Kamphuis et al., RECOVERY OF STORAGE AND EMPTYING FUNCTIONS OF THE URINARY-BLADDER AFTER SPINAL-ANESTHESIA WITH LIDOCAINE AND WITH BUPIVACAINE IN MEN, Anesthesiology, 88(2), 1998, pp. 310-316
Background: The aim of this study was to evaluate and compare the effe
cts of spinal anesthesia with lidocaine and with bupivacaine on urinar
y bladder function in healthy men who were scheduled for minor orthopa
edic surgical procedures. Methods: Twenty men were randomly allocated
to receive either bupivacaine or lidocaine. Before spinal anesthesia,
filling cystometry was performed with the patient in the supine positi
on and a pressure flow study was done with the patient in the standing
position. After operation, cystometric measurements were continued un
til the patient could void urine spontaneously. The levels of analgesi
a and of motor blockade were recorded. Results: The urge to void disap
peared immediately after Injection of the local anesthetics. There was
no difference in the duration of lower extremity motor blockade betwe
en bupivacaine and lidocaine, Detrusor blockade lasted significantly l
onger in the bupivacaine group (means +/- SD, 460 +/- 60 min) than in
the lidocaine group (235 +/- 30 min). Total fluid intake and urine vol
ume accumulated during the detrusor blockade were significantly higher
in the bupivacaine group than in the lidocaine group. In the bupivaca
ine group, the total volume of accumulated mine (875 +/- 385 ml) was a
lso significantly higher than cystometric bladder capacity (505 +/- 12
0 ml) with the risk of over distension of the bladder. Spontaneous voi
ding of urine did not occur until segmental sensory analgesia had regr
essed to the third sacral segment. Conclusions: Spinal anesthesia with
lidocaine and with bupivacaine causes a clinically significant distur
bance of bladder function due to interruption of the micturition refle
x. The urge to void disappears quickly and bladder function remains im
paired until the block has regressed to the third sacral segment in al
l patients. With long-acting local anesthetics, the volume of accumula
ted urine may exceed the cystometric bladder capacity. With respect to
recovery of urinary bladder function, the use of short-acting local a
nesthetics for spinal anesthesia seems to be preferable.