Non-Hodgkin's lymphoma is not commonly a familial condition. This is b
elieved to be the first two cases of primary pancreatic lymphoma withi
n a single family. The two cases, a brother and sister, both presented
in their 60s and were diagnosed histologically as having high grade B
cell lymphoma affecting the pancreas, an uncommon primary site. Both
responded well to treatment with chemotherapy and were in remission at
-the time of writing. On further investigation it was found that their
mother also presented with a malignant lymphoma of cervical nodes 30
years earlier and subsequently died of the disease.