ARE INTRINSIC INHIBITORY SYSTEMS ACTIVATED OR INHIBITED IN PATHOLOGICAL PAIN STATES

Authors
OMOTE K
Citation
K. Omote, ARE INTRINSIC INHIBITORY SYSTEMS ACTIVATED OR INHIBITED IN PATHOLOGICAL PAIN STATES, Behavioral and brain sciences, 20(3), 1997, pp. 461
Citations number
10
Categorie Soggetti
Psychology, Biological",Neurosciences,"Behavioral Sciences
Journal title
Behavioral and brain sciences → ACNP
ISSN journal
0140525X
Volume
20
Issue
3
Year of publication
1997
Database
ISI
SICI code
0140-525X(1997)20:3<461:AIISAO>2.0.ZU;2-P
Abstract
Neuroplastic changes in the inhibitory systems contribute to pathologi cal pains such as hyperalgesia. Activation or inhibition of the intrin sic inhibitory systems may depend on the pathophysiology which induces a sustained pain state. The mechanisms of hyperalgesia, opioid insens itivity following nerve injury, and opioid tolerance may be related to common neuroplastic changes.