Certain patients with a possible contribution of the sympathetic syste
m to pain may not fit the definition of complex regional pain syndrome
s (CRPS), which raises the question of terminology for those patients.
To further clarify the relationship between the sympathetic system an
d pain, apart from the need for placebo studies, there remains an urge
nt need for a satisfactory definition of the criteria for a complete s
ympathetic block. It also remains uncertain whether a change in the di
scharge pattern of sympathetic fibres underlies the changes in sympath
etic organ function, often found in patients with CRPS.