METERED-DOSE INHALER - PAST, PRESENT, AND FUTURE

Background: The metered dose inhaler (MDI) to treat respiratory diseas es was introduced many years ago. Due to the recently proposed ban on chlorofluorocarbon (Freon) production, the survival of the conventiona l MDI is uncertain. It is therefore incumbent on asthma caretakers to familiarize themselves with newer versions of the inhaler. Objective: To review the different modalities of aerosolized treatment employed i n the management of asthma. This article is specifically focused on is sues related to MDIs, the propellants, and the modifications since its introduction. Data Source: The MEDLINE database was used to review MD I related literature in the English language. Conclusion: Dry powder i nhalers (especially the multi-dose type) and Freon-free pressurized MD Is appear promising and probably will replace conventional freon-prope lled pressurized MDIs when Freon is no longer available.