M. Bohme et Hi. Huppertz, NEUROBORRELIOSIS WITH EDEMA OF THE OPTIC DISK AND PARALYSIS OF THE NERVUS ABDUCENS, Monatsschrift fur Kinderheilkunde, 146(1), 1998, pp. 17-19
We report on two children (7-year-old girl; 11-year-old boy) with an u
nusual manifestation of neuroborreliosis involving the nervus opticus
and nervus abducens. Both children had a bilateral oedema of the optic
disk and a strabismus convergens caused by paralysis of the 6th crani
al nerve. Since, in addition, the children presented with headache, in
itially an intracranial tumor was considered but then excluded by magn
etic resonance imaging. The cerebrospinal fluid showed a mononuclear p
leocytosis,and specific antibodies against Borrelia burgdorferi were d
etected in serum and in CSF. These results confirmed the diagnosis of
''neuroborreliosis''. All clinical manifestations disappeared a few da
ys to weeks after treatment with intravenous ceftriaxon. Discussion: I
n the presence of cranial nerve palsy and optic disk oedema of unknown
origin neuroborreliosis may be the correct diagnosis. Isolated involv
ement of the eye in the late stage of Lyme borreliosis is distinct fro
m neuroborreliosis with cranial nerve involvement.