With the methods available today, most patients who arrive at the emer
gency department with acute cardiogenic pulmonary edema can be treated
quickly and effectively. Modern pharmacologic therapy is based on dir
ectly counteracting the physiologic abnormalities that cause pulmonary
edema. Agents that are useful in reducing LV preload and afterload an
d in managing hypotension are nitroglycerin, ACE inhibitors, vasodilat
ors, vasopressors, and bipyrines. Noninvasive pressure support ventila
tion helps patients with pulmonary edema by decreasing the work of bre
athing, enhancing oxygen and carbon dioxide exchange, and increasing c
ardiac output. Use of BiPAP systems in emergency departments has avert
ed endotracheal intubation in about 90% of patients with pulmonary ede
ma who are experiencing acute respiratory failure.(23,24).