CONFORMATION ANALYSIS OF INTERMEDIATES OF ANALOGS OF TAMOXIFEN

Authors
KAPILLERDEZSOFI R NEMETH G LAX G SIMIG G SOHAR P
Citation
R. Kapillerdezsofi et al., CONFORMATION ANALYSIS OF INTERMEDIATES OF ANALOGS OF TAMOXIFEN, Journal of molecular structure, 441(1), 1998, pp. 89-92
Citations number
5
Categorie Soggetti
Chemistry Physical
Journal title
Journal of molecular structure → ACNP
ISSN journal
00222860
Volume
441
Issue
1
Year of publication
1998
Pages
89 - 92
Database
ISI
SICI code
0022-2860(1998)441:1<89:CAOIOA>2.0.ZU;2-R
Abstract
The configuration and the conformation of two trifluoromethyl-triaryl- ethane diastereomer pairs and of some sole isomers were determined usi ng the through-space spin-spin coupling between fluorine atoms and the hydrogen of the hydroxyl group. The molecule-mechanical calculations support the results of the conformation-analysis based on the NMR data . (C) 1998 Elsevier Science B.V.