Rheumatoid arthritis most often affects the cervical spine, resulting
in clinical and radiographic findings. For most patients with rheumato
id arthritis the cervical involvement represents a relatively benign p
rocess, but, in a small percentage of these patients, a progressive in
stability pattern develops that may compromise neural or vascular stru
ctures. The rate of neural compromise because of cervical instability
ranges from 11% to 58%. The clinical manifestation may be radiculopath
y, myelopathy, quadriplegia, and, in extreme instances, sudden death.