ONE-POT MITSUNOBU-STAUDINGER PREPARATION OF 3-AMINOCHOLAN-24-OIC ACID-ESTERS FROM 3-HYDROXYCHOLAN-24-OIC ACID-ESTERS

Authors
ANELLI PL LATTUADA L UGGERI F
Citation
Pl. Anelli et al., ONE-POT MITSUNOBU-STAUDINGER PREPARATION OF 3-AMINOCHOLAN-24-OIC ACID-ESTERS FROM 3-HYDROXYCHOLAN-24-OIC ACID-ESTERS, Synthetic communications, 28(1), 1998, pp. 109-117
Citations number
23
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthetic communications → ACNP
ISSN journal
00397911
Volume
28
Issue
1
Year of publication
1998
Pages
109 - 117
Database
ISI
SICI code
0039-7911(1998)28:1<109:OMPO3A>2.0.ZU;2-S
Abstract
3-Hydroxycholan-24-oic acid esters are easily converted into the corre sponding 3-amino derivatives via Mitsunobu reaction with diphenylphosp horyl azide (DPPA) and Staudinger reduction with PPh3/H2O of the inter mediate azido compound in THF.