In recent years, researchers in the psychosocial and biomedical scienc
es have become increasingly aware of the importance of sample-size cal
culations in the design of research projects. Such considerations are,
however, rarely applied for studies involving agreement of raters. Pu
blished results on this topic are limited and generally provide rather
complex formulas. In addition, they generally make the assumption tha
t the raters have the same set of frequencies for the possible ratings
. In this article I show that for the case of 2 raters and 2 possible
ratings the assumptions of equal frequencies can be dropped. Tables th
at allow for almost immediate sample-size determination for a variety
of common study designs are given.