BACKGROUND: Stromal tumors of the digestive tract are undifferentiated
connective tissue tumors which are difficult to characterize even wit
h immunohistochemistry. CASE REPORT: A stromal tumor of the duodenum (
the most frequently encountered location) was resected entirely. Histo
chemistry was unable to provide a precise identification of the histol
ogical nature. The tumor was considered to be low grade due to the low
mitosis index despite its large size and the presence of necrosis. Ca
reful surveillance was indicated. DISCUSSION: The risk of these tumors
is uncertain and may be assessed on the basis of histological prognos
is factors such as tumor size, mitosis index and ploidy. Echoendoscopy
can be particularly useful for diagnostic purposes providing informat
ion on location in the duodenal musculosa.