MOLECULAR-CLONING OF CISH, CHROMOSOME ASSIGNMENT TO 3P21.3, AND ANALYSIS OF EXPRESSION IN FETAL AND ADULT TISSUES

Authors
UCHIDA K YOSHIMURA A INAZAWA J YANAGISAWA K OSADA H MASUDA A SAITO T TAKAHASHI T MIYAJIMA A TAKAHASHI T
Citation
K. Uchida et al., MOLECULAR-CLONING OF CISH, CHROMOSOME ASSIGNMENT TO 3P21.3, AND ANALYSIS OF EXPRESSION IN FETAL AND ADULT TISSUES, Cytogenetics and cell genetics, 78(3-4), 1997, pp. 209-212
Citations number
10
Categorie Soggetti
Cell Biology","Genetics & Heredity
Journal title
Cytogenetics and cell genetics → ACNP
ISSN journal
03010171
Volume
78
Issue
3-4
Year of publication
1997
Pages
209 - 212
Database
ISI
SICI code
0301-0171(1997)78:3-4<209:MOCCAT>2.0.ZU;2-M
Abstract
The murine cytokine inducible SH2-containing (Cis) protein gene (Cish) was recently cloned and shown to have a growth inhibitory function. W e have isolated cDNAs coding for its human homologue (CISH) and assign ed the gene to 3p21.3 by fluorescence in situ hybridization. Northern blot analysis showed CISH expression in various epithelial tissues inc luding lung and kidney, in which tumors frequently exhibit 3p21.3 dele tions.