THE SH3D1A GENE MAPS TO HUMAN-CHROMOSOME 21Q22.1-]Q22.2

Authors
CHEN H ANTONARAKIS SE
Citation
H. Chen et Se. Antonarakis, THE SH3D1A GENE MAPS TO HUMAN-CHROMOSOME 21Q22.1-]Q22.2, Cytogenetics and cell genetics, 78(3-4), 1997, pp. 213-215
Citations number
14
Categorie Soggetti
Cell Biology","Genetics & Heredity
Journal title
Cytogenetics and cell genetics → ACNP
ISSN journal
03010171
Volume
78
Issue
3-4
Year of publication
1997
Pages
213 - 215
Database
ISI
SICI code
0301-0171(1997)78:3-4<213:TSGMTH>2.0.ZU;2-Q
Abstract
Exon trapping was used to identify portions of genes on human chromoso me 21. BLAST search of databases revealed that the trapped sequence hm c02a08 (one of 559 different trapped exons) was identical to a region of GenBank entry U61166 for an SH3 (Src-homology) domain-containing ge ne SH3D1A (formerly called SH3P17; Sparks et al., 1996). We subsequent ly mapped this gene to YACs and cosmids within 21q22.1-->q22.2 between DNA markers D21S319 and D21S65 using hybridization and PCR amplificat ion.