Two patients with chronic hiccup and MRI demonstrated lesions at the l
evel oi the inferior olivary complex are here reported. Whereas the ne
urological examination was normal in case 1, case 2 had the syndrome o
f palatal myoclonus and progressive ataxia. In the case I, extensive e
lectrophysiological studies were consistent with hiccup, in the absenc
e of any other disorder (in particular, there was no evidence of palat
al myoclonus). These findings suggest that the dysfunction of:he infer
ior olivary complex could be implicated in the pathogenesis of hiccup.