THE FACILE AND EFFICIENT SYNTHESIS OF 8-CHLOROADENOSINE 3',5'-CYCLIC-MONOPHOSPHATE BY PHOSPHORYLATIVE CYCLIZATION OF 8-CHLOROADENOSINE AND ITS CHARACTERIZATION BY H-1 AND C-13 NMR-SPECTROSCOPY

Authors
WOO NT JIN SY CHO DJ KIM NS BAE EH JUNG JH HAM H JUNG YH
Citation
Nt. Woo et al., THE FACILE AND EFFICIENT SYNTHESIS OF 8-CHLOROADENOSINE 3',5'-CYCLIC-MONOPHOSPHATE BY PHOSPHORYLATIVE CYCLIZATION OF 8-CHLOROADENOSINE AND ITS CHARACTERIZATION BY H-1 AND C-13 NMR-SPECTROSCOPY, Archives of pharmacal research, 20(2), 1997, pp. 176-179
Citations number
9
Categorie Soggetti
Biology
Journal title
Archives of pharmacal research → ACNP
ISSN journal
02536269
Volume
20
Issue
2
Year of publication
1997
Pages
176 - 179
Database
ISI
SICI code
0253-6269(1997)20:2<176:TFAESO>2.0.ZU;2-B
Abstract
Purine nucleosides were chlorinated by the reaction of acyl chloride i n DMF with MCPBA under mild conditions with moderate yields. And, sati sfactory method for the synthesis of ribonucleoside-3',5'-cyclic phosp hates and its characterization by H-1 and C-13 nmr spectroscopy is des cribed.