Nf. Dekeizer et al., HEALTH-STATUS PREDICTION IN CRITICALLY ILL CHILDREN - A PILOT-STUDY INTRODUCING STANDARDIZED HEALTH RATIOS, Quality of life research, 6(2), 1997, pp. 192-199
Performance of intensive care is usually quantified by means of standa
rdized mortality rates, where standardization is directed towards the
severity of illness on admission. However, as more critically ill pati
ents survive, functional outcome and quality of life of these patients
becomes more important. In a prospective study in a 10-bed tertiary p
aediatric intensive care unit (ICU), admission and follow-up health st
atus were collected for 209 surviving patients. For this cohort of pat
ients, health status 1 year after admission was also predicted, using
the quantified health-utility-index (HUI), as a Value between 0 and 1.
For this purpose, two alternative multiple regression models were con
structed. The most important predictors of 1-year health status were t
he level of sensation, mobility and cognition on admission to which se
lf-care, systolic blood pressure, oxygen, Glascow Coma Scale, glucose
and age may be added. The two alternative predictive models performed
equally well (R-2 = 0.83 and 0.84 respectively), indicating that healt
h status could be predicted to a significant degree, The concept of re
lating expected future health status (based on base-line health status
), with actual (observed) health status is denoted with the Standardiz
ed Health Ratio (SHR). In combination with the Standardized Mortality
Ratios (SMR), such a ratio may become a new comprehensive indicator of
performance in intensive care medicine.