MECHANISM OF THE YEAST MEDIATED REDUCTION OF NITROSTYRENES IN LIGHT PETROLEUM

Authors
MCANDA AF ROBERTS KD SMALLRIDGE AJ TEN A TREWHELLA MA
Citation
Af. Mcanda et al., MECHANISM OF THE YEAST MEDIATED REDUCTION OF NITROSTYRENES IN LIGHT PETROLEUM, Journal of the Chemical Society. Perkin transactions. I, (3), 1998, pp. 501-504
Citations number
14
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of the Chemical Society. Perkin transactions. I → ACNP
ISSN journal
0300922X
Issue
3
Year of publication
1998
Pages
501 - 504
Database
ISI
SICI code
0300-922X(1998):3<501:MOTYMR>2.0.ZU;2-Y
Abstract
The yeast mediated reduction of a range of alpha- and beta-deutero sub stituted nitrostyrenes has been conducted in light petroleum in the pr esence of a small amount of water or D2O. NMR analysis of the products from these reactions has allowed the determination of the mechanism o f this yeast reduction reaction. The results indicate that initially, a reversible non-stereoselective protonation occurs at the beta-centre , followed by stereoselective addition of hydride at the alpha-positio n.