Ng. Kundu et al., PALLADIUM-CATALYZED HETEROANNULATION WITH TERMINAL ALKYNES - SYNTHESIS OF PHTHALIDES, Journal of the Chemical Society. Perkin transactions. I, (3), 1998, pp. 561-568
The palladium-copper-catalysed heteroannulation of o-iodobenzoic acid
3 with terminal alkynes 4-18 leads to the synthesis of (Z)-3-alkyliden
ephthalides 19-33 as the major products. In certain cases, the formati
on of isocoumarins 34-37 is also observed.