L. Puig et al., CALCINOSIS CUTIS FOLLOWING CALCIUM-CHLORIDE ELECTRODE PASTE APPLICATION FOR AUDITORY-BRAIN-STEM EVOKED-POTENTIALS RECORDING, Pediatric dermatology, 15(1), 1998, pp. 27-30
Circumscribed calcification in the dermis (calcinosis cutis) has been
reported following electroencephalographic and electromyographic studi
es at sites of electrode placement following application of an electro
de paste containing calcium chloride. Prolonged exposure and skin micr
oabrasions seem to increase the risk of this rare complication of elec
trode placement, which has not been previously reported following audi
tory brainstem evoked potential recordings. We report the appearance o
f localized dermal calcifications at the sites of electrode placement
(forehead and retroauricular areas) following auditory brainstem evoke
d potential recordings in two children, aged 3 and 2 years, respective
ly. In both cases the electrodes were applied after gentle scrubbing w
ith an ethanol-impregnated gauze and interposition of a calcium chlori
de bentonite magma paste. The recording took about 1 hour. Erythematou
s macules and plaques ranging from 4 to 12 mm in diameter, studded wit
h small stony excrescences, appeared at the areas of electrode applica
tion I and 5 days later, respectively. Histopathologic study of 4 mm p
unch biopsy specimens showed amorphous dermal deposits of calcium salt
s. There was superficial ulceration and transepidermal elimination of
the calcium deposits, as well as a foreign body tissue reaction in the
surrounding dermis. In both patients small stony pellets were extrude
d during the healing process, which took 11 and 9 weeks, respectively,
and left no scars.