DIAMOND-GARDNER-SYNDROME - A CASE-REPORT

We present a 13-year-old girl who came to our attention for an erythem atous bruised lesion which appeared spontaneously without any apparent coagulopathy. The history, histology, and positive ''skin-test,'' car ried out by subcutaneously injecting autologous erythrocytes obtained from heparinized blood, confirmed the suspected diagnosis of Diamond-G ardner syndrome. No alterations of blood vessel walls or thromboses we re found. Evaluation of hemocoagulative parameters revealed an increas ed factor VIII level and reduced platelet aggregation after stimulatio n by adenosine diphosphate (ADP).