A working model for treating spasticity with botulinum toxin A has bee
n adopted by the National Hospital for Neurology and Neurosurgery in L
ondon, United Kingdom. To achieve functional goals with this toxin, al
l the factors contributing to spasticity must be considered; the toxin
must be given as part of a complete neurorehabilitative programme wit
h clear symptomatic or functional goals. Although experience with the
use of this agent in spasticity is growing, many functional benefits o
f the therapy are still unclear. A trial of botulinum toxin A as part
of neurorehabilitation is currently being undertaken at the National H
ospital for Neurology and Neurosurgery.