The early phase of psychosis may be considered as a critical period th
at offers major opportunities for secondary prevention of impairments
and disabilities accompanying psychosis. Prospective studies of first-
episode schizophrenics support the critical period hypothesis and indi
cate that progression, where it occurs, does so early in the disorder,
with patients reaching a relatively stable plateau within 2 years of
the first psychotic episode. This suggests a window of opportunity for
secondary prevention. Particular intervention strategies may be appro
priate early in the disorder, such as early detection and prevention o
f relapse and cognitive therapy within an acute psychotic episode to r
educe early treatment resistance. (C) 1998 Rapid Science Ltd.