Spinal lesions were reviewed in 9 patients (3 men and 6 women) who pre
sented with palmoplantar pustulosis. Cervical lesions were found in 3
patients and lumbosacral involvement in 7. The duration of disease ave
raged 4.8 years. Seven patients had associated sterno-costo-clavicular
hyperostotic lesions, and all showed abnormalities in blood tests whi
ch suggested chronic inflammation. Vertebral Lesions were assessed as
a spondylodiscitis type in 4, single level syndesmophyte-forming type
in 1, multiple hyperostosis type in 4, and an ivory vertebra type in 1
. Five patients were treated conservatively and 4 with progressive spo
ndylodiscitis type lesions underwent curettage and anterior interbody
fusions. At follow-up, all patients improved in both spinal and cutane
ous presentations, and 4 who underwent surgery and 1 with tonsillectom
y attained complete cure. The vertebral manifestations of palmoplantar
pustulosis may vary, but rapidly progressive lesions need surgery for
favourable early improvement from the vertebro-cutaneous symptom comp
lex.