EFFECTS OF DIETHYL-DITHIOCARBAMATE ON ANTIOXIDANT SYSTEM IN CARP TISSUE

The influence the pro- and antioxidant values the diethyl-dithiocarbam ate (DDTC) in different concentrations in carp tissues was studied. Fr om antioxidant enzymes superoxide dismutase, catalase and glutathion p eroxidase activity changes were studied in tissue homogenates. Beside enzyme activities tissue lipid peroxidation (LP), reduced glutathione (GSH) and hydroxyl radical loading of the tissues were measured. Our r esults indicate that DDTC affects antioxidant parameters by generating GSH excess, not loading the cells thereby with ''oxidative stress''.