NONPROGRESSIVE CMV RETINITIS IN AIDS PATIENTS WITH PROTEASE INHIBITORS THERAPY FOR AIDS

Cytomegalovirus (CMV) retinitis is the most common opportunistic viral infection in acquired immunodeficiency syndrome (AIDS) patients with a low CD4+ count. Without specific treatment, the disease is an import ant cause of blindness. We report two cases of AIDS with nonprogressiv e CMV retinitis after undergoing a combined antiHIV treatment schedule including at least one protease inhibitor. The treatment was associat ed with an increase in circulating CD4+ lymphocytes. This newly availa ble antiviral combination may well prevent the recurrence of CMV disea se and decrease the morbidity of CMV retinitis.