Jdd. Aunon et al., LICHEN MYXOEDEMATOSUS ASSOCIATED WITH HUMAN-IMMUNODEFICIENCY-VIRUS INFECTION - REPORT OF 2 CASES AND REVIEW OF THE LITERATURE, Clinical and experimental dermatology, 22(6), 1997, pp. 265-268
Lichen myxoedematosus (LM), or papular mucinosis, is an uncommon papul
ar eruption caused by the dermal deposition of mucin. Three clinical f
orms can be distinguished, namely localised, disseminated (involving m
ore than one site), and generalised LM, the last is called scleromyxoe
dema, and demonstrates erythema and skin sclerosis.(1) Paraproteinaemi
a, often consisting of an abnormal IgG with lambda light chains, is us
ually present in patients with LM.(2) Visceral involvement has also be
en documented.(3) An association between LM and human immunodeficiency
virus (HIV) infection has been reported recently We now describe two
further HIV-positive patients with LM and present a review-of-the lite
rature regarding this association.