Sl. Woodrow et Se. Handfieldjones, ENLARGING CONGENITAL HEMANGIOMA IN AN ADULT - A NEW ENTITY, Clinical and experimental dermatology, 22(6), 1997, pp. 283-286
We report the case of a 39-year-old woman with a persistent congenital
vascular lesion, which unusually is continuing to enlarge. Histologic
ally, the lesion is a thin-walled haemangioma with numerous mast cells
. Currently, the precise mechanism of vessel proliferation in such les
ions is unknown, but it is important in the pathogenesis of both haema
ngiomas and other dermatological conditions, as well as in wound heali
ng and the formation of tumour metastases. We discuss various angiogen
ic factors with particular reference to the putative role of the mast
cell in the pathogenesis of haemangiomas.