Hypomelanosis of Ito (HOI) is a neurocutaneous disorder which clinical
ly is a well-characterised disease, in which chromosomal instability m
ay be a component.(1,2) Various neurological and other non-cutaneous m
alformations have been reported in association with the char acteristi
c swirling pattern of hypopigmentation.(3) We report two cases of this
rare condition, one with hitherto unreported associations.