A STRAIN PEDIOCOCCUS SP. ISK-1 ISOLATED FROM NUKADOKO PRODUCES A NOVEL BACTERIOCIN

Pediococcus sp. ISK-1 isolated in our laboratory from well-aged Nukado ko, produces a bacteriocin which has a unique antimicrobial spectrum a mong pediocins. The antimicrobial activity was detected at the late ex ponential growth phase during fermentation and reached the maximum at the late stationary phase. The bacteriocin was stable at acidic pH, an d more than 60% of the antimicrobial activity still remained even afte r being autoclaved at 121 degrees C for 20 min in the pH range of 3 to 8. This is the first report dealt with bacteriocin produced by lactic acid bacteria isolated from Nukadoko.