AN INHIBITOR OF ALDOSE REDUCTASE AND SORBITOL ACCUMULATION FROM ANTHOCEPHARUS-CHINENSIS

Authors
HARAGUCHI H KANADA M FUKUDA A NARUSE K OKAMURA N YAGI A
Citation
H. Haraguchi et al., AN INHIBITOR OF ALDOSE REDUCTASE AND SORBITOL ACCUMULATION FROM ANTHOCEPHARUS-CHINENSIS, Planta medica, 64(1), 1998, pp. 68-69
Citations number
15
Categorie Soggetti
Pharmacology & Pharmacy","Plant Sciences","Chemistry Medicinal
Journal title
Planta medica → ACNP
ISSN journal
00320943
Volume
64
Issue
1
Year of publication
1998
Pages
68 - 69
Database
ISI
SICI code
0032-0943(1998)64:1<68:AIOARA>2.0.ZU;2-2
Abstract
A flavonoid glycoside was isolated from Anthocepharus chinensis. Its s tructure was elucidated by spectral data and determined to be myriceti n 3-O-(4 ''-acetyl)-alpha-fucoside. This flavonoid glycoside and its a glycone showed potent inhibition against rat and lens aldose reductase . The flavonoid aglycone also inhibited sorbitol accumulation in human red blood cells.