TOWARDS DESIGN AND COMPARISON OF WORLD-WIDE WEB-ACCESSIBLE MYOCARDIAL2-DIMENSIONAL GEL-ELECTROPHORESIS PROTEIN DATABASES

In addition to the recently published HEART-2DPAGE - a myocardial Worl d Wide Web-accessible 2-DE gel protein database - the usage and instal lation of software tools are described with regard to the hard- and so ftware environments. Further, access to the HEART-2DPAGE from other tw o-dimensional electrophoresis (2-DE) databases using name or accession code of a protein is now available. Moreover, database images, publis hed in the myocardial HSC-2DPAGE and HEART-2DPAGE databases are compar ed. Using the warping tool of the common image processing system Khoro s the database images are matched and added in order to visualize the effects of warping. The application of such Image processing tools is aimed al improving the comparability of protein spot patterns of diffe rent gel images available through the net.