A STEREOSELECTIVE SYNTHESIS OF TRANS-1,2-DISUBSTITUTED ALKENES BASED ON THE CONDENSATION OF ALDEHYDES WITH METALATED 1-PHENYL-1H-TETRAZOL-5-YL SULFONES

Authors
BLAKEMORE PR COLE WJ KOCIENSKI PJ MORLEY A
Citation
Pr. Blakemore et al., A STEREOSELECTIVE SYNTHESIS OF TRANS-1,2-DISUBSTITUTED ALKENES BASED ON THE CONDENSATION OF ALDEHYDES WITH METALATED 1-PHENYL-1H-TETRAZOL-5-YL SULFONES, Synlett, (1), 1998, pp. 26
Citations number
12
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
1
Year of publication
1998
Database
ISI
SICI code
0936-5214(1998):1<26:ASSOTA>2.0.ZU;2-X
Abstract
The reaction of metallated 1-phenyl-1H-tetrazol-5-yl sulfones and alde hydes gives good yields and stereoselectivity of trans-1,2-disubstitut ed alkenes when potassium or sodium hexamethyldisilazide is used as ba se and 1,2-dimethoxyethane is used as solvent.